منابع مشابه
2D and 3D Self-Assembling Nanofiber Hydrogels for Cardiomyocyte Culture
Collagen is a widely used biomaterial in cardiac tissue engineering studies. However, as a natural material, it suffers from variability between batches that can complicate the standardization of culture conditions. In contrast, synthetic materials are modifiable, have well-defined structures and more homogeneous batches can be produced. In this study, several collagen-like synthetic self-assem...
متن کاملthree-dimensional (3d) cell culture conditions, present and future improvements
conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...
متن کاملA modular flow-chamber bioreactor concept as a tool for continuous 2D- and 3D-cell culture
Background Advanced cell culture models, especially long-term 3D systems, require bioreactors allowing for cultivation under continuous flow conditions. Such culture models are for example tissue engineered implants, 3D cultures for drug testing, in vitro models of cell growth and migration for wound healing studies, cell cultures for biomaterial testing. New challenges in drug testing and biom...
متن کاملMultiscale iterative voting for differential analysis of stress response for 2D and 3D cell culture models.
Three-dimensional (2D) cell culture models have emerged as the basis for improved cell systems biology. However, there is a gap in robust computational techniques for segmentation of these model systems that are imaged through confocal or deconvolution microscopy. The main issues are the volume of data, overlapping subcellular compartments and variation in scale or size of subcompartments of in...
متن کاملGradient lithography of engineered proteins to fabricate 2D and 3D cell culture microenvironments
Spatial patterning of proteins is a valuable technique for many biological applications and is the prevailing tool for defining microenvironments for cells in culture, a required procedure in developmental biology and tissue engineering research. However, it is still challenging to achieve protein patterns that closely mimic native microenvironments, such as gradient protein distributions with ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biopolymers and Cell
سال: 2011
ISSN: 0233-7657,1993-6842
DOI: 10.7124/bc.00007d